By night, Sayaka Sakurai works as a teacher at a certain school. A stunning beauty who draws attention from countless students, her true identity remains a secret—she is in fact the alien warrior "Spandexer Saint Angel," hailing from a distant galaxy. Unbeknownst to everyone around her, she continues her daily routine teaching classes. Meanwhile, the villainous Gerhardt plots to conquer Earth by launching a comet missile toward the planet. The last hope for survival, the Cybertron 379, has suddenly been stolen. Witnessing this catastrophe, a female scientist pleads with Saint Angel to recover the stolen Cybertron. Thus begins a thrilling saga of conflict and hope spanning across the cosmos and Earth.